| datum | match | uitslag |
| 06-08-21 20u45 | Cl. Brugge - Ce. Brugge | - |
| 07-08-21 16u15 | Beerschot - Union | - |
| 07-08-21 18u30 | STVV - Z-Waregem | - |
| 07-08-21 18u30 | Mechelen - Eupen | - |
| 07-08-21 20u45 | Kortrijk - Genk | - |
| 08-08-21 13u30 | Standard - Antwerp | - |
| 08-08-21 16u00 | OH Leuven - Charleroi | - |
| 08-08-21 18u30 | Anderlecht - Seraing | - |
| 08-08-21 21u00 | Oostende - Gent | - |
| datum | speeldag | match |
| 07-08-21 20u45 | 03 | Kortrijk - Genk |
| 14-08-21 20u45 | 04 | Genk - OH Leuven |
| 22-08-21 21u00 | 05 | Antwerp - Genk |
| 29-08-21 18u30 | 06 | Genk - Anderlecht |
| 11-09-21 18u30 | 07 | Genk - Union |
| 18-09-21 18u30 | 08 | STVV - Genk |
| 25-09-21 18u30 | 09 | Genk - Seraing |
| 02-10-21 18u30 | 10 | Eupen - Genk |
| 16-10-21 18u30 | 11 | Charleroi - Genk |
| 23-10-21 18u30 | 12 | Genk - Gent |
| ploeg | m | w | g | v | gv | gt | s | p | ||
| 1 |
 |
Kortrijk | 2 | 2 | 0 | 0 | 3 | 0 | 3 | 6 |
| 2 |
 |
Charleroi | 2 | 1 | 1 | 0 | 3 | 0 | 3 | 4 |
| 3 |
 |
Cl. Brugge | 2 | 1 | 1 | 0 | 3 | 2 | 1 | 4 |
| 4 |
 |
Standard | 2 | 1 | 1 | 0 | 3 | 2 | 1 | 4 |
| 5 |
 |
Ce. Brugge | 2 | 1 | 1 | 0 | 2 | 1 | 1 | 4 |
| 6 |
 |
STVV | 2 | 1 | 1 | 0 | 2 | 1 | 1 | 4 |
| 7 |
 |
Union | 2 | 1 | 0 | 1 | 3 | 2 | 1 | 3 |
| 8 |
 |
Mechelen | 2 | 1 | 0 | 1 | 3 | 3 | 0 | 3 |
| 9 |
 |
Seraing | 2 | 1 | 0 | 1 | 1 | 2 | -1 | 3 |
| 10 |
 |
Oostende | 2 | 1 | 0 | 1 | 4 | 6 | -2 | 3 |
| 11 |
 |
Eupen | 2 | 0 | 2 | 0 | 3 | 3 | 0 | 2 |
| 12 |
 |
OH Leuven | 2 | 0 | 2 | 0 | 2 | 2 | 0 | 2 |
| 13 |
 |
Genk | 2 | 0 | 1 | 1 | 4 | 5 | -1 | 1 |
| 14 |
 |
Gent | 2 | 0 | 1 | 1 | 3 | 4 | -1 | 1 |
| 15 |
 |
Beerschot | 2 | 0 | 1 | 1 | 2 | 3 | -1 | 1 |
| 16 |
 |
Z-Waregem | 2 | 0 | 1 | 1 | 2 | 3 | -1 | 1 |
| 17 |
 |
Anderlecht | 2 | 0 | 1 | 1 | 2 | 4 | -2 | 1 |
| 18 |
 |
Antwerp | 2 | 0 | 0 | 2 | 2 | 4 | -2 | 0 |
